Diphthamide is a post-translationally modified histidine residue present in elongation factor 2, and is the target of diphtheria toxin. This gene encodes a protein that contains a WD-40 domain, and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase, converting methylated diphthine to diphthine, which can then undergo amidation to produce diphthamide. [provided by RefSeq, Oct 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DPH7-20-RE | 20 (40 μL) | 200 μL |  |
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| DPH7-20-OR | 20 (40 μL) | 200 μL |  |
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| DPH7-20-GO | 20 (40 μL) | 200 μL |  |
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| DPH7-20-GR | 20 (40 μL) | 200 μL |  |
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| DPH7-20-AQ | 20 (40 μL) | 200 μL |  |
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Diphthamide is a post-translationally modified histidine residue present in elongation factor 2, and is the target of diphtheria toxin. This gene encodes a protein that contains a WD-40 domain, and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase, converting methylated diphthine to diphthine, which can then undergo amidation to produce diphthamide. [provided by RefSeq, Oct 2016]
Gene Symbol : DPH7
Gene Name : Diphthamide biosynthesis 7
Chromosome : CHR 9: 137,578,934-137,554,898
Locus : 9q34.3
Alt. Genes : FEM1B
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