Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
DPM3-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
DPM3-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
DPM3-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
DPM3-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
DPM3-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008]
Gene Symbol : DPM3
Gene Name : Dolichyl-phosphate mannosyltransferase subunit 3
Chromosome : CHR 1: 155,140,572-155,139,890
Locus : 1q22
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