This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DPP10-20-RE | 20 (40 μL) | 200 μL |  |
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| DPP10-20-OR | 20 (40 μL) | 200 μL |  |
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| DPP10-20-GO | 20 (40 μL) | 200 μL |  |
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| DPP10-20-GR | 20 (40 μL) | 200 μL |  |
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| DPP10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : DPP10
Gene Name : Dipeptidyl peptidase like 10
Chromosome : CHR 2: 114,442,357-115,845,751
Locus : 2q14.1
Alt. Genes : LRPPRC
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