This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DRD3-20-RE | 20 (40 μL) | 200 μL |  |
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| DRD3-20-OR | 20 (40 μL) | 200 μL |  |
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| DRD3-20-GO | 20 (40 μL) | 200 μL |  |
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| DRD3-20-GR | 20 (40 μL) | 200 μL |  |
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| DRD3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
Gene Symbol : DRD3
Gene Name : Dopamine receptor D3
Chromosome : CHR 3: 114,199,406-114,127,622
Locus : 3q13.31
Alt. Genes : FEM1B
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