This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DRD4-20-RE | 20 (40 μL) | 200 μL |  |
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| DRD4-20-OR | 20 (40 μL) | 200 μL |  |
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| DRD4-20-GO | 20 (40 μL) | 200 μL |  |
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| DRD4-20-GR | 20 (40 μL) | 200 μL |  |
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| DRD4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
Gene Symbol : DRD4
Gene Name : Dopamine receptor D4
Chromosome : CHR 11: 637,304-640,705
Locus : 11p15.5
Alt. Genes : CHST4
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