The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DSCR3-20-RE | 20 (40 μL) | 200 μL |  |
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| DSCR3-20-OR | 20 (40 μL) | 200 μL |  |
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| DSCR3-20-GO | 20 (40 μL) | 200 μL |  |
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| DSCR3-20-GR | 20 (40 μL) | 200 μL |  |
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| DSCR3-20-AQ | 20 (40 μL) | 200 μL |  |
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The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]
Gene Symbol : DSCR3
Gene Name : DSCR3 arrestin fold containing
Chromosome : CHR 21: 372,681,23-372,234,24
Locus : 21q22.13
Alt. Genes : MKRN3-AS1
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