Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DUSP14-20-RE | 20 (40 μL) | 200 μL |  |
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| DUSP14-20-OR | 20 (40 μL) | 200 μL |  |
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| DUSP14-20-GO | 20 (40 μL) | 200 μL |  |
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| DUSP14-20-GR | 20 (40 μL) | 200 μL |  |
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| DUSP14-20-AQ | 20 (40 μL) | 200 μL |  |
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Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
Gene Symbol : DUSP14
Gene Name : Dual specificity phosphatase 14
Chromosome : CHR 17: 374,885,60-375,135,00
Locus : 17q12
Alt. Genes : FEM1B
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