This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DYNC2LI1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DYNC2LI1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DYNC2LI1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DYNC2LI1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| DYNC2LI1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Symbol : DYNC2LI1
Gene Name : Dynein cytoplasmic 2 light intermediate chain 1
Chromosome : CHR 2: 437,740,38-438,284,91
Locus : 2p21
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.