This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DYRK3-20-RE | 20 (40 μL) | 200 μL |  |
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| DYRK3-20-OR | 20 (40 μL) | 200 μL |  |
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| DYRK3-20-GO | 20 (40 μL) | 200 μL |  |
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| DYRK3-20-GR | 20 (40 μL) | 200 μL |  |
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| DYRK3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : DYRK3
Gene Name : Dual specificity tyrosine phosphorylation regulated kinase 3
Chromosome : CHR 1: 206,635,535-206,655,157
Locus : 1q32.1
Alt. Genes : YAF2
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