This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| E2F3-20-RE | 20 (40 μL) | 200 μL |  |
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| E2F3-20-OR | 20 (40 μL) | 200 μL |  |
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| E2F3-20-GO | 20 (40 μL) | 200 μL |  |
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| E2F3-20-GR | 20 (40 μL) | 200 μL |  |
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| E2F3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Gene Symbol : E2F3
Gene Name : E2F transcription factor 3
Chromosome : CHR 6: 203,532,84-204,937,13
Locus : 6p22.3
Alt. Genes : DNAL4
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