The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ECT2-20-RE | 20 (40 μL) | 200 μL |  |
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| ECT2-20-OR | 20 (40 μL) | 200 μL |  |
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| ECT2-20-GO | 20 (40 μL) | 200 μL |  |
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| ECT2-20-GR | 20 (40 μL) | 200 μL |  |
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| ECT2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Gene Symbol : ECT2
Gene Name : Epithelial cell transforming 2
Chromosome : CHR 3: 172,750,681-172,829,272
Locus : 3q26.31
Alt. Genes : LRPPRC
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