The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EGLN2-20-RE | 20 (40 μL) | 200 μL |  |
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| EGLN2-20-OR | 20 (40 μL) | 200 μL |  |
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| EGLN2-20-GO | 20 (40 μL) | 200 μL |  |
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| EGLN2-20-GR | 20 (40 μL) | 200 μL |  |
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| EGLN2-20-AQ | 20 (40 μL) | 200 μL |  |
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The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]
Gene Symbol : EGLN2
Gene Name : Egl-9 family hypoxia inducible factor 2
Chromosome : CHR 19: 407,991,42-408,084,40
Locus : 19q13.2
Alt. Genes : CEBPZ
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