This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EHD2-20-RE | 20 (40 μL) | 200 μL |  |
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| EHD2-20-OR | 20 (40 μL) | 200 μL |  |
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| EHD2-20-GO | 20 (40 μL) | 200 μL |  |
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| EHD2-20-GR | 20 (40 μL) | 200 μL |  |
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| EHD2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008]
Gene Symbol : EHD2
Gene Name : EH domain containing 2
Chromosome : CHR 19: 477,133,43-477,431,33
Locus : 19q13.33
Alt. Genes : AASS
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