This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EIF2AK4-20-RE | 20 (40 μL) | 200 μL |  |
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| EIF2AK4-20-OR | 20 (40 μL) | 200 μL |  |
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| EIF2AK4-20-GO | 20 (40 μL) | 200 μL |  |
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| EIF2AK4-20-GR | 20 (40 μL) | 200 μL |  |
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| EIF2AK4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
Gene Symbol : EIF2AK4
Gene Name : Eukaryotic translation initiation factor 2 alpha kinase 4
Chromosome : CHR 15: 399,341,00-400,355,95
Locus : 15q15.1
Alt. Genes : MKRN3-AS1
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