The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EIF2B3-20-RE | 20 (40 μL) | 200 μL |  |
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| EIF2B3-20-OR | 20 (40 μL) | 200 μL |  |
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| EIF2B3-20-GO | 20 (40 μL) | 200 μL |  |
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| EIF2B3-20-GR | 20 (40 μL) | 200 μL |  |
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| EIF2B3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Symbol : EIF2B3
Gene Name : Eukaryotic translation initiation factor 2B subunit gamma
Chromosome : CHR 1: 449,867,21-448,505,21
Locus : 1p34.1
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