The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EIF4E-20-RE | 20 (40 μL) | 200 μL |  |
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| EIF4E-20-OR | 20 (40 μL) | 200 μL |  |
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| EIF4E-20-GO | 20 (40 μL) | 200 μL |  |
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| EIF4E-20-GR | 20 (40 μL) | 200 μL |  |
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| EIF4E-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Gene Symbol : EIF4E
Gene Name : Eukaryotic translation initiation factor 4E
Chromosome : CHR 4: 989,306,34-988,784,55
Locus : 4q23
Alt. Genes : G3BP1
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