The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EIF4G3-20-RE | 20 (40 μL) | 200 μL |  |
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| EIF4G3-20-OR | 20 (40 μL) | 200 μL |  |
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| EIF4G3-20-GO | 20 (40 μL) | 200 μL |  |
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| EIF4G3-20-GR | 20 (40 μL) | 200 μL |  |
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| EIF4G3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
Gene Symbol : EIF4G3
Gene Name : Eukaryotic translation initiation factor 4 gamma 3
Chromosome : CHR 1: 211,773,19-208,062,91
Locus : 1p36.12
Alt. Genes : ZNF263
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