The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ELF5-20-RE | 20 (40 μL) | 200 μL |  |
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| ELF5-20-OR | 20 (40 μL) | 200 μL |  |
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| ELF5-20-GO | 20 (40 μL) | 200 μL |  |
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| ELF5-20-GR | 20 (40 μL) | 200 μL |  |
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| ELF5-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
Gene Symbol : ELF5
Gene Name : E74 like ETS transcription factor 5
Chromosome : CHR 11: 345,137,99-344,787,90
Locus : 11p13
Alt. Genes : RBM12
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