The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ELP1-20-RE | 20 (40 μL) | 200 μL |  |
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| ELP1-20-OR | 20 (40 μL) | 200 μL |  |
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| ELP1-20-GO | 20 (40 μL) | 200 μL |  |
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| ELP1-20-GR | 20 (40 μL) | 200 μL |  |
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| ELP1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Gene Symbol : ELP1
Gene Name : Elongator complex protein 1
Chromosome : CHR 9: 108,934,331-108,867,519
Locus : 9q31.3
Alt. Genes : PREB
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