ENPP2 FISH Probe

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ENPP2-20-RE 20 (40 μL) 200 μL color Request Pricing
ENPP2-20-OR 20 (40 μL) 200 μL color Request Pricing
ENPP2-20-GO 20 (40 μL) 200 μL color Request Pricing
ENPP2-20-GR 20 (40 μL) 200 μL color Request Pricing
ENPP2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]

Gene Details

Gene Symbol : ENPP2

Gene Name : Ectonucleotide pyrophosphatase/phosphodiesterase 2

Chromosome : CHR 8: 119,673,403-119,557,076

Locus : 8q24.12

Alt. Genes : ENAM

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