This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERAP2-20-RE | 20 (40 μL) | 200 μL |  |
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| ERAP2-20-OR | 20 (40 μL) | 200 μL |  |
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| ERAP2-20-GO | 20 (40 μL) | 200 μL |  |
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| ERAP2-20-GR | 20 (40 μL) | 200 μL |  |
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| ERAP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]
Gene Symbol : ERAP2
Gene Name : Endoplasmic reticulum aminopeptidase 2
Chromosome : CHR 5: 968,759,39-969,197,02
Locus : 5q15
Alt. Genes : FLOT1
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