This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERBIN-20-RE | 20 (40 μL) | 200 μL |  |
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| ERBIN-20-OR | 20 (40 μL) | 200 μL |  |
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| ERBIN-20-GO | 20 (40 μL) | 200 μL |  |
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| ERBIN-20-GR | 20 (40 μL) | 200 μL |  |
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| ERBIN-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Symbol : ERBIN
Gene Name : Erbb2 interacting protein
Chromosome : CHR 5: 659,265,53-660,810,23
Locus : 5q12.3
Alt. Genes : ENAM
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