The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERCC4-20-RE | 20 (40 μL) | 200 μL |  |
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| ERCC4-20-OR | 20 (40 μL) | 200 μL |  |
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| ERCC4-20-GO | 20 (40 μL) | 200 μL |  |
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| ERCC4-20-GR | 20 (40 μL) | 200 μL |  |
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| ERCC4-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009]
Gene Symbol : ERCC4
Gene Name : ERCC excision repair 4, endonuclease catalytic subunit
Chromosome : CHR 16: 139,201,37-139,523,47
Locus : 16p13.12
Alt. Genes : FEM1B
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