This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ESX1-20-RE | 20 (40 μL) | 200 μL |  |
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| ESX1-20-OR | 20 (40 μL) | 200 μL |  |
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| ESX1-20-GO | 20 (40 μL) | 200 μL |  |
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| ESX1-20-GR | 20 (40 μL) | 200 μL |  |
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| ESX1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010]
Gene Symbol : ESX1
Gene Name : ESX homeobox 1
Chromosome : CHR X: 104,254,917-104,250,037
Locus : Xq22.2
Alt. Genes : TRIM13
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