The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EXO5-20-RE | 20 (40 μL) | 200 μL |  |
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| EXO5-20-OR | 20 (40 μL) | 200 μL |  |
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| EXO5-20-GO | 20 (40 μL) | 200 μL |  |
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| EXO5-20-GR | 20 (40 μL) | 200 μL |  |
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| EXO5-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]
Gene Symbol : EXO5
Gene Name : Exonuclease 5
Chromosome : CHR 1: 405,087,18-405,165,55
Locus : 1p34.2
Alt. Genes : AASS
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