The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
FASN-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
FASN-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
FASN-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
FASN-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
FASN-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
Gene Symbol : FASN
Gene Name : Fatty acid synthase
Chromosome : CHR 17: 820,983,02-820,783,37
Locus : 17q25.3
Alt. Genes : ZNF263
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