The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FASTK-20-RE | 20 (40 μL) | 200 μL |  |
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| FASTK-20-OR | 20 (40 μL) | 200 μL |  |
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| FASTK-20-GO | 20 (40 μL) | 200 μL |  |
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| FASTK-20-GR | 20 (40 μL) | 200 μL |  |
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| FASTK-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : FASTK
Gene Name : Fas activated serine/threonine kinase
Chromosome : CHR 7: 151,080,882-151,076,620
Locus : 7q36.1
Alt. Genes : SUGP2
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