This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FAT2-20-RE | 20 (40 μL) | 200 μL |  |
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| FAT2-20-OR | 20 (40 μL) | 200 μL |  |
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| FAT2-20-GO | 20 (40 μL) | 200 μL |  |
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| FAT2-20-GR | 20 (40 μL) | 200 μL |  |
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| FAT2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]
Gene Symbol : FAT2
Gene Name : FAT atypical cadherin 2
Chromosome : CHR 5: 151,594,821-151,504,091
Locus : 5q33.1
Alt. Genes : OPTN
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