This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBLIM1-20-RE | 20 (40 μL) | 200 μL |  |
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| FBLIM1-20-OR | 20 (40 μL) | 200 μL |  |
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| FBLIM1-20-GO | 20 (40 μL) | 200 μL |  |
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| FBLIM1-20-GR | 20 (40 μL) | 200 μL |  |
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| FBLIM1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : FBLIM1
Gene Name : Filamin binding LIM protein 1
Chromosome : CHR 1: 157,561,70-157,865,89
Locus : 1p36.21
Alt. Genes : TRAP1
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