Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBXL12-20-RE | 20 (40 μL) | 200 μL |  |
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| FBXL12-20-OR | 20 (40 μL) | 200 μL |  |
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| FBXL12-20-GO | 20 (40 μL) | 200 μL |  |
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| FBXL12-20-GR | 20 (40 μL) | 200 μL |  |
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| FBXL12-20-AQ | 20 (40 μL) | 200 μL |  |
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Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Symbol : FBXL12
Gene Name : F-box and leucine rich repeat protein 12
Chromosome : CHR 19: 982,052,6-981,026,6
Locus : 19p13.2
Alt. Genes : RBM12
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