This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBXL8-20-RE | 20 (40 μL) | 200 μL |  |
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| FBXL8-20-OR | 20 (40 μL) | 200 μL |  |
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| FBXL8-20-GO | 20 (40 μL) | 200 μL |  |
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| FBXL8-20-GR | 20 (40 μL) | 200 μL |  |
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| FBXL8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008]
Gene Symbol : FBXL8
Gene Name : F-box and leucine rich repeat protein 8
Chromosome : CHR 16: 671,599,87-671,641,73
Locus : 16q22.1
Alt. Genes : HNRNPA3P1
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