Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBXW10-20-RE | 20 (40 μL) | 200 μL |  |
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| FBXW10-20-OR | 20 (40 μL) | 200 μL |  |
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| FBXW10-20-GO | 20 (40 μL) | 200 μL |  |
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| FBXW10-20-GR | 20 (40 μL) | 200 μL |  |
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| FBXW10-20-AQ | 20 (40 μL) | 200 μL |  |
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Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Symbol : FBXW10
Gene Name : F-box and WD repeat domain containing 10
Chromosome : CHR 17: 187,440,12-187,793,48
Locus : 17p11.2
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