This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FES-20-RE | 20 (40 μL) | 200 μL |  |
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| FES-20-OR | 20 (40 μL) | 200 μL |  |
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| FES-20-GO | 20 (40 μL) | 200 μL |  |
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| FES-20-GR | 20 (40 μL) | 200 μL |  |
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| FES-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]
Gene Symbol : FES
Gene Name : FES proto-oncogene, tyrosine kinase
Chromosome : CHR 15: 908,844,20-908,957,75
Locus : 15q26.1
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