This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FEZ1-20-RE | 20 (40 μL) | 200 μL |  |
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| FEZ1-20-OR | 20 (40 μL) | 200 μL |  |
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| FEZ1-20-GO | 20 (40 μL) | 200 μL |  |
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| FEZ1-20-GR | 20 (40 μL) | 200 μL |  |
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| FEZ1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : FEZ1
Gene Name : Fasciculation and elongation protein zeta 1
Chromosome : CHR 11: 125,496,309-125,445,744
Locus : 11q24.2
Alt. Genes : ENAM
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