This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FGA-20-RE | 20 (40 μL) | 200 μL |  |
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| FGA-20-OR | 20 (40 μL) | 200 μL |  |
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| FGA-20-GO | 20 (40 μL) | 200 μL |  |
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| FGA-20-GR | 20 (40 μL) | 200 μL |  |
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| FGA-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016]
Gene Symbol : FGA
Gene Name : Fibrinogen alpha chain
Chromosome : CHR 4: 154,590,765-154,583,125
Locus : 4q31.3
Alt. Genes : OPTN
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