This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FHL2-20-RE | 20 (40 μL) | 200 μL |  |
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| FHL2-20-OR | 20 (40 μL) | 200 μL |  |
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| FHL2-20-GO | 20 (40 μL) | 200 μL |  |
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| FHL2-20-GR | 20 (40 μL) | 200 μL |  |
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| FHL2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2016]
Gene Symbol : FHL2
Gene Name : Four and a half LIM domains 2
Chromosome : CHR 2: 105,438,772-105,360,825
Locus : 2q12.2
Alt. Genes : ZNF263
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