The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FKBP1B-20-RE | 20 (40 μL) | 200 μL |  |
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| FKBP1B-20-OR | 20 (40 μL) | 200 μL |  |
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| FKBP1B-20-GO | 20 (40 μL) | 200 μL |  |
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| FKBP1B-20-GR | 20 (40 μL) | 200 μL |  |
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| FKBP1B-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : FKBP1B
Gene Name : FK506 binding protein 1B
Chromosome : CHR 2: 240,332,04-240,677,42
Locus : 2p23.3
Alt. Genes : HIPK3
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