This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FLI1-20-RE | 20 (40 μL) | 200 μL |  |
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| FLI1-20-OR | 20 (40 μL) | 200 μL |  |
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| FLI1-20-GO | 20 (40 μL) | 200 μL |  |
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| FLI1-20-GR | 20 (40 μL) | 200 μL |  |
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| FLI1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Symbol : FLI1
Gene Name : Fli-1 proto-oncogene, ETS transcription factor
Chromosome : CHR 11: 128,685,262-128,813,266
Locus : 11q24.3
Alt. Genes : HIPK3
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