This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FLNB-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| FLNB-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| FLNB-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| FLNB-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| FLNB-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
Gene Symbol : FLNB
Gene Name : Filamin B
Chromosome : CHR 3: 580,083,99-581,722,54
Locus : 3p14.3
Alt. Genes : YAF2
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.