This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FLNC-20-RE | 20 (40 μL) | 200 μL |  |
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| FLNC-20-OR | 20 (40 μL) | 200 μL |  |
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| FLNC-20-GO | 20 (40 μL) | 200 μL |  |
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| FLNC-20-GR | 20 (40 μL) | 200 μL |  |
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| FLNC-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : FLNC
Gene Name : Filamin C
Chromosome : CHR 7: 128,830,428-128,859,273
Locus : 7q32.1
Alt. Genes : OPTN
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