This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
FMO2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
FMO2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
FMO2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
FMO2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
FMO2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Gene Symbol : FMO2
Gene Name : Flavin containing monooxygenase 2
Chromosome : CHR 1: 171,185,207-171,212,682
Locus : 1q24.3
Alt. Genes : FARP1
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