This gene encodes a protein containing two tryptophan-rich WW domains that binds the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration. It also binds intersectin family proteins suggesting a role in the maintenance of membrane curvature at sites of nascent vesicle formation. Naturally occurring mutations in this gene are associated with Waardenburg anophthalmia syndrome. [provided by RefSeq, Apr 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FNBP4-20-RE | 20 (40 μL) | 200 μL |  |
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| FNBP4-20-OR | 20 (40 μL) | 200 μL |  |
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| FNBP4-20-GO | 20 (40 μL) | 200 μL |  |
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| FNBP4-20-GR | 20 (40 μL) | 200 μL |  |
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| FNBP4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein containing two tryptophan-rich WW domains that binds the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration. It also binds intersectin family proteins suggesting a role in the maintenance of membrane curvature at sites of nascent vesicle formation. Naturally occurring mutations in this gene are associated with Waardenburg anophthalmia syndrome. [provided by RefSeq, Apr 2017]
Gene Symbol : FNBP4
Gene Name : Formin binding protein 4
Chromosome : CHR 11: 477,674,77-477,165,09
Locus : 11p11.2
Alt. Genes : ZNF263
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