This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FNIP1-20-RE | 20 (40 μL) | 200 μL |  |
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| FNIP1-20-OR | 20 (40 μL) | 200 μL |  |
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| FNIP1-20-GO | 20 (40 μL) | 200 μL |  |
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| FNIP1-20-GR | 20 (40 μL) | 200 μL |  |
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| FNIP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
Gene Symbol : FNIP1
Gene Name : Folliculin interacting protein 1
Chromosome : CHR 5: 131,797,062-131,641,713
Locus : 5q31.1
Alt. Genes : LRPPRC
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