This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FNIP2-20-RE | 20 (40 μL) | 200 μL |  |
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| FNIP2-20-OR | 20 (40 μL) | 200 μL |  |
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| FNIP2-20-GO | 20 (40 μL) | 200 μL |  |
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| FNIP2-20-GR | 20 (40 μL) | 200 μL |  |
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| FNIP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
Gene Symbol : FNIP2
Gene Name : Folliculin interacting protein 2
Chromosome : CHR 4: 158,768,994-158,908,049
Locus : 4q32.1
Alt. Genes : LRPPRC
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