This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FPGS-20-RE | 20 (40 μL) | 200 μL |  |
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| FPGS-20-OR | 20 (40 μL) | 200 μL |  |
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| FPGS-20-GO | 20 (40 μL) | 200 μL |  |
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| FPGS-20-GR | 20 (40 μL) | 200 μL |  |
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| FPGS-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
Gene Symbol : FPGS
Gene Name : Folylpolyglutamate synthase
Chromosome : CHR 9: 127,802,857-127,814,519
Locus : 9q34.11
Alt. Genes : HIPK3
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