This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
FTO-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
FTO-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
FTO-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
FTO-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
FTO-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Gene Symbol : FTO
Gene Name : FTO, alpha-ketoglutarate dependent dioxygenase
Chromosome : CHR 16: 537,039,62-541,144,66
Locus : 16q12.2
Alt. Genes : FEM1B
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