This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FYCO1-20-RE | 20 (40 μL) | 200 μL |  |
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| FYCO1-20-OR | 20 (40 μL) | 200 μL |  |
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| FYCO1-20-GO | 20 (40 μL) | 200 μL |  |
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| FYCO1-20-GR | 20 (40 μL) | 200 μL |  |
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| FYCO1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]
Gene Symbol : FYCO1
Gene Name : FYVE and coiled-coil domain containing 1
Chromosome : CHR 3: 459,958,23-459,178,98
Locus : 3p21.31
Alt. Genes : ZNF263
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