This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FZD8-20-RE | 20 (40 μL) | 200 μL |  |
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| FZD8-20-OR | 20 (40 μL) | 200 μL |  |
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| FZD8-20-GO | 20 (40 μL) | 200 μL |  |
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| FZD8-20-GR | 20 (40 μL) | 200 μL |  |
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| FZD8-20-AQ | 20 (40 μL) | 200 μL |  |
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This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : FZD8
Gene Name : Frizzled class receptor 8
Chromosome : CHR 10: 356,414,33-356,382,48
Locus : 10p11.21
Alt. Genes : LPCAT3
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