This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| G6PC2-20-RE | 20 (40 μL) | 200 μL |  |
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| G6PC2-20-OR | 20 (40 μL) | 200 μL |  |
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| G6PC2-20-GO | 20 (40 μL) | 200 μL |  |
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| G6PC2-20-GR | 20 (40 μL) | 200 μL |  |
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| G6PC2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : G6PC2
Gene Name : Glucose-6-phosphatase catalytic subunit 2
Chromosome : CHR 2: 168,901,222-168,909,999
Locus : 2q31.1
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