This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GABRG3-20-RE | 20 (40 μL) | 200 μL |  |
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| GABRG3-20-OR | 20 (40 μL) | 200 μL |  |
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| GABRG3-20-GO | 20 (40 μL) | 200 μL |  |
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| GABRG3-20-GR | 20 (40 μL) | 200 μL |  |
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| GABRG3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Gene Symbol : GABRG3
Gene Name : Gamma-aminobutyric acid type A receptor gamma3 subunit
Chromosome : CHR 15: 269,712,81-275,371,11
Locus : 15q12
Alt. Genes : LINC01587
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